Scientific Archives
Abstract Archives
Allen, M.J., Schoonmaker, J.E., Mann, K.A., Ross, V., Allen, C., Morley, P., Willick, G.E. and Whitfield, J.F. PTH analogs enhance bone formation at a weight-bearing cement-bone interface. Orthopedics Research Society, 2004.
Jolette, J., Smith, S.Y., Mayer, J., Green, C., Rushton, B. and Morley, P. Ostabolin-C™: A novel parathyroid hormone analogue uncouples bone turnover in monkeys. 25th Annual Meeting of the American Society of Bone and Mineral Research, Minneapolis, Minnesota, September 19-23, 2003.
Allen, C.M., Chakravarthy, B., Morley, P., Whitfield, J.F. and Willick, G.E. hPTH-(1-34) and hPTH-(1-31)NH2 prevent phosphate from killing MC3T3-E1 preosteoblasts and HKRKB7 pig kidney cells. American Society of Bone and Mineral Research, San Antonio, Texas, September 20-24, 2002.
Mehta, N.M., Gilligan, J.P., Stern, B., Ray, M.V.L., Meenan, C.P., Consalvo, A.P., Peng, X., Vignery, A., Ross, V., Whitfield, J.F. and Morley, P. Biological activity of recombinant PTH analog UGL7841. American Society of Bone and Mineral Research, San Antonio, Texas, September 20-24, 2002.
Research Paper Archives
Whitfield, J.F., Bird, R.P., Morley, P., Willick, G.E., Barbier, J.-R., MacLean, S. and Ross, V. The effects of parathyroid hormone (PTH) fragments on bone formation and the initiation of colon carcinogenesis in rats as indicated by preneoplastic aberrant crypt formation. Cancer Letters 200:107-113, 2003.
Whitfield, J.F., Morley, P. and Willick, G.E. The parathyroid hormone, its fragments and their analogs for treating osteoporosis. Treatments in Endocrinology 1:175-190, 2002.
Whitfield, J.F., Morley, P. and Willick, G.E. The control of bone growth by parathyroid hormone, leptin and statins. Critical Reviews of Eukaryotic Gene Expression 12:23-51, 2002.
Whitfield, J.F., Morley, P. and Willick, G.E. Bone growth stimulators: New tools for treating bone loss and mending fractures. Vitamins and Hormones 65:1-80, 2002
Whitfield, J.F. A New Member of the Bone Builders' Club? Medscape Women's Health E-Journal 7(4), 2002.
Whitfield, J.F., Morley, P., Willick, G.E., The Control of Bone Growth by PTH, Leptin, & Statins, Critical Reviews in Eukaryotic Gene Expression, Vol.12, Iss. 1, pp:23-51, 2002.
Whitfield, J.F., Morley, P., Willick, G.E. PTH, Its Fragments and Their Analogs for the Treatment of Osteoporosis, Treat Endocrinol, Vol. 1, No.3, pp:175-190, 2002.
Morley, P., Whitfield, J.F. and Willick, G.E. Therapeutic prospects for parathyroid hormone and parathyroid hormone analogues. Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents (submitted), 2001.
Morley, P., Whitfield, J.F., Willick, G.E., Ross, V., MacLean, S., Barbier, J.-R., Isaacs, R.J. and Andreassen, T.T. The effect of monocyclic and bicyclic analogues of human parathyroid hormone hPTH-(1-31)NH2 on bone formation and mechanical strength in ovariectomized rats. Calcified Tissue International 68:95-101, 2001.
Morley, P., Whitfield, J.F., Willick, G.E. PTH: An Anabolic Treatment for Osteoporosis, Current Pharmaceutical design, Vol.7, No.8, pp:671-687, 2001.
Whitfield, J.F., Morley, P., Willick, G.E., Isaacs, R.J., MacLean, S., Ross, V., Barbier, J.-R., Divieti, P., Bringhurst F.R. Lactam formation increases receptor binding, adenylyl cyclase stimulation and bone growth stimulation by human parathyroid hormone (hPTH)-(1-28)NH2. Journal of Bone and Mineral Research 15:964-970, 2000.
Fraher, L.J., Avram, R., Watson, P.H., Hendy, G.N., Henderson, J.E., Goltzman, D., Morley, P., Whitfield, J.F. and Hodsman, A.B. A comparison of the biochemical responses to 1-31 parathyroid hormone and 1-34 parathyroid hormone in healthy humans. Journal of Clinical Endocrinology and Metabolism 84: 2739-2743, 1999.
Whitfield, J.F., Morley, P., Fraher, L., Hodsman, A.B., Watson, P.H., Holdsworth, D., Gulam, M., Willick, G.E., Barbier, J.-R., Isaacs, R.J., MacLean, S. and Ross, V. The stimulation of vertebral and tibial bone growth by the parathyroid hormone (PTH) fragments, hPTH-(1-31)NH2, [Leu27]-cyclo(Glu22-Lys26)-hPTH-(1-31)NH2, and hPTH-(1-34). Calcified Tissue International 66:307-312, 1999.
Morley, P., Whitfield, J.F., Willick, G.E., Ross, V., MacLean, S., Isaacs, R.J., Mendoza, E. and Barbier, J.-R. Prolonged low-dose infusion of human parathyroid hormone does not increase femoral cancellous bone volume in ovariectomized rats. European Journal of Endocrinology 141: 70-74, 1999.
Whitfield, J.F., Morley, P., Willick G., MacLean, S., Ross, V., Isaacs, R.J. and Barbier, J.-R. Comparison of the abilities of human parathyroid hormone (hPTH)-(1-34) and [Leu27]-cyclo(Glu22-Lys26)-hPTH-(1-31)NH2 to stimulate femoral trabecular bone growth in ovariectomized rats. Calcified Tissue International 63: 423-428, 1998.
Whitfield, J.F., Morley, P., Willick, G.E., Langille, R., Ross, V., MacLean, S. and Barbier, J.-R. Cyclization by a specific lactam linkage increases the ability of human parathyroid hormone (hPTH)-(1-31)NH2 to stimulate bone growth in ovariectomized rats. Journal of Bone and Mineral Research 12: 1246-1252, 1997.
Whitfield, J.F., Morley, P., Willick, G.E., Ross, V., MacLean, S., Barbier, J.-R., Isaacs, R.J. and Ohannessian-Barry, L. Comparison of the abilities of a recombinant human parathyroid hormone, rhPTH-(1-84), and hPTH-(1-31)NH2 (Ostabolin) to stimulate femoral trabecular bone growth in ovariectomized rats. Calcified Tissue International 60: 26-29, 1997.
Whitfield, J.F., Morley, P., Willick, G.E., Ross, V., Barbier, J.R., Isaacs, R.J. and Ohannesian-Barry, L. Stimulation of the growth of femoral trabecular bone in ovariectomized rats by the novel parathyroid hormone fragment, hPTH-(1-31)NH2 (Ostabolin). Calcified Tissue International 58:81-87, 1996.
Jouishomme, H., Whitfield, J.F., Chakravarthy, B., Durkin, J.P., Gagnon, L., Isaacs, R.J., MacLean, S., Neugebauer, W., Willick, G. and Rixon, R.H. The protein kinase C activation domain of the parathyroid hormone. Endocrinology 130:53-60, 1992.
